An immunoresponsive three-dimensional urine-tolerant human urothelial model to study urinary tract infection

IntroductionMurine models of urinary tract infection (UTI) have improved our understanding of host-pathogen interactions. However, given differences between rodent and human bladders which may modulate host and bacterial response, including certain biomarkers, urothelial thickness and the concentrat...

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Bibliographic Details
Main Authors: Nazila V. Jafari, Jennifer L. Rohn
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1128132/full