Branched-chain amino acids catabolism and cancer progression: focus on therapeutic interventions

Branched-chain amino acids (BCAAs), including valine, leucine, and isoleucine, are crucial amino acids with significant implications in tumorigenesis across various human malignancies. Studies have demonstrated that altered BCAA metabolism can influence tumor growth and progression. Increased levels...

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Bibliographic Details
Main Authors: Er Xu, Bangju Ji, Ketao Jin, Yefeng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1220638/full