Functional imaging with dual-energy computed tomography for supplementary non-invasive assessment of mast cell burden in systemic mastocytosis

Abstract Systemic mastocytosis (SM) is characterized by multifocal accumulation of neoplastic mast cells (MCs), predominately affecting the bone marrow (BM). Imaging with computed tomography (CT) is used for assessment of bone mineral density and structure. However, the value of functional imaging w...

Full description

Bibliographic Details
Main Authors: Julia Riffel, Johannes Lübke, Nicole Naumann, Sebastian Kreil, Georgia Metzgeroth, Alice Fabarius, Karl Sotlar, Hans-Peter Horny, Mohamad Jawhar, Daniel Overhoff, Stefan Schoenberg, Wolf-Karsten Hofmann, Thomas Henzler, Juliana Schwaab, Andreas Reiter, Philipp Riffel
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18537-6