Population Dynamics of Epithelial-Mesenchymal Heterogeneity in Cancer Cells

Phenotypic heterogeneity is a hallmark of aggressive cancer behaviour and a clinical challenge. Despite much characterisation of this heterogeneity at a multi-omics level in many cancers, we have a limited understanding of how this heterogeneity emerges spontaneously in an isogenic cell population....

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Bibliographic Details
Main Authors: Paras Jain, Sugandha Bhatia, Erik W. Thompson, Mohit Kumar Jolly
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/3/348