Contrasting roles of donor and recipient TGFB1 and IFNG gene polymorphic variants in chronic kidney transplant rejection

Contrasting roles of donor and recipient TGFB1 and IFNG gene polymorphic variants in chronic kidney transplant rejection

ABSTRACT Objective: To assess the long-term impact (minimum of 3 years follow-up) of polymorphisms in cytokine genes in donor:recipient pairs on the results of the transplant. Methods: We compared genetic cytokine polymorphisms and the primary factors of risk for the development of chronic rejecti...

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Bibliographic Details
Main Authors: Verônica Porto Carreiro de Vasconcellos Coelho, Rafael Ioschpe, Cristina Caldas, Monica Spadafora-Ferreira, João Americo Fonseca, Maria Regina Alves Cardoso, Selma Aliotti Palacios, Jorge Kalil, Anna Carla Goldberg
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2011-03-01
Series:Einstein (São Paulo)
Subjects:
Chronic renal allograft dysfunction
Genetic polymorphism
Donor genotype
Transforming growth factor beta-1
Interferon-gamma
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000100046&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000100046&tlng=en

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