Spatial and Temporal Heterogeneity in Clonal Evolution of Nonsmall-cell Lung Cancer: Implications for Therapy

Tumoral heterogeneity has been associated with treatment resistance and failure in patients with cancer. Tumoral heterogeneity can be either intertumoral (static variation of cancer cells) or intratumoral (spatial and temporal variation of cancer cells). Nonsmall-cell lung cancer (NSCLC) is consider...

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Bibliographic Details
Main Authors: Koulouris A., Tsagkaris C., Mountzios G.
Format: Article
Language:English
Published: Sciendo 2023-10-01
Series:Forum of Clinical Oncology
Subjects:
Online Access:https://doi.org/10.2478/fco-2023-0005