Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma

Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma

Summary: Lactate is known to play a crucial role in the progression of malignancies. However, its mechanism in regulating the malignant phenotype of head and neck squamous cell carcinoma (HNSCC) remains unclear. This study found that lactate increases cancer stem cell (CSC) characteristics of HNSCC...

Full description

Bibliographic Details
Main Authors: Yunqing Sun, Yang Chen, Hui Zhao, Jingjing Wang, Yuantong Liu, Junqiang Bai, Chuanyu Hu, Zhengjun Shang
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Cellular physiology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224005613

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224005613

Similar Items