Green synthesis of 2-trifluoromethyl quinoline derivatives under metal-free conditions and their antifungal properties

Green synthesis of 2-trifluoromethyl quinoline derivatives under metal-free conditions and their antifungal properties

The skeleton of 2-trifluoromethyl quinoline is the core structure of many natural products and pharmaceutical molecules. The synthesis of this scaffold is limited by metal catalysis, harsh conditions, toxic or hazardous reagents and solvents, and lower atom-economy. Herein, a novel method for the sy...

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Bibliographic Details
Main Authors: Liangxin Fan, Fangyu He, Lijun Shi, Guoyu Yang, Zhenliang Pan, Miaomiao Wang, Caixia Wang, Lulu Wu, Senyu Han, Yifang Guo, Cuilian Xu
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Saudi Chemical Society
Subjects:
2-trifluoromethyl quinolines
Metal-catalyst-free
O-aminobenzaldehydes
1,3-diketones
Antifungal activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610323001655

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http://www.sciencedirect.com/science/article/pii/S1319610323001655

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