Green synthesis of 2-trifluoromethyl quinoline derivatives under metal-free conditions and their antifungal properties
The skeleton of 2-trifluoromethyl quinoline is the core structure of many natural products and pharmaceutical molecules. The synthesis of this scaffold is limited by metal catalysis, harsh conditions, toxic or hazardous reagents and solvents, and lower atom-economy. Herein, a novel method for the sy...
Main Authors: | Liangxin Fan, Fangyu He, Lijun Shi, Guoyu Yang, Zhenliang Pan, Miaomiao Wang, Caixia Wang, Lulu Wu, Senyu Han, Yifang Guo, Cuilian Xu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-11-01
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Series: | Journal of Saudi Chemical Society |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610323001655 |
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