Synthesis of Novel C/D Ring Modified Bile Acids

Synthesis of Novel C/D Ring Modified Bile Acids

Bile acid receptors have been identified as important targets for the development of new therapeutics to treat various metabolic and inflammatory diseases. The synthesis of new bile acid analogues can help elucidate structure–activity relationships and define compounds that activate these receptors...

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Bibliographic Details
Main Authors: Roselis A. Landaeta Aponte, Andreas Luxenburger, Scott A. Cameron, Alex Weymouth-Wilson, Richard H. Furneaux, Lawrence D. Harris, Benjamin J. Compton
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
bile acid
zinc carbenoids
cyclopropane
rearrangement
drug discovery
Online Access:https://www.mdpi.com/1420-3049/27/7/2364

Internet

https://www.mdpi.com/1420-3049/27/7/2364

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