Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome

Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome

Abstract Obesity during pregnancy leads to adverse health outcomes in offspring. However, the initial effects of maternal obesity (MO) on embryonic organogenesis have yet to be thoroughly examined. Using unbiased single‐cell transcriptomic analyses (scRNA‐seq), the effects of MO on the myogenic proc...

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Bibliographic Details
Main Authors: Liang Zhao, Nathan C. Law, Noe A. Gomez, Junseok Son, Yao Gao, Xiangdong Liu, Jeanene M. de Avila, Mei‐Jun Zhu, Min Du
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Advanced Science
Subjects:
bone morphogenetic proteins signaling
embryonic myogenesis
maternal obesity
single cell RNA sequencing
Online Access:https://doi.org/10.1002/advs.202102157

Internet

https://doi.org/10.1002/advs.202102157

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