Comparative Effectiveness Randomized Clinical Trial Using Next-generation Microbial Sequencing to Direct Prophylactic Antibiotic Choice Before Urologic Stone Lithotripsy Using an Interprofessional Model

Comparative Effectiveness Randomized Clinical Trial Using Next-generation Microbial Sequencing to Direct Prophylactic Antibiotic Choice Before Urologic Stone Lithotripsy Using an Interprofessional Model

Background: Next-generation sequencing (NGS) methods for microbial profiling have increased sensitivity to detect urinary pathogens. Objective: To determine whether NGS microbial profiling can be used to guide antibiotic prophylaxis and reduce infection compared with the standard of care. Design, se...

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Bibliographic Details
Main Authors: Michael A. Liss, Kelly R. Reveles, Craig D. Tipton, Jonathan Gelfond, Timothy Tseng
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:European Urology Open Science
Subjects:
Kidney stone
Lithotripsy
Next-generation sequencing
Microbiome
Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2666168323010820

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http://www.sciencedirect.com/science/article/pii/S2666168323010820

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