Deletion of lymphotoxin-β receptor (LTβR) protects against acute kidney injury by PPARα pathway

Abstract Background Recent data has shown a considerable advancement in understanding the role of lymphotoxin-β receptor (LTβR) in inflammation. However, the functions and underlying mechanisms of LTβR in acute kidney injury (AKI) remain largely unknown. Methods AKI was induced in mice by renal isch...

Full description

Bibliographic Details
Main Authors: Zufeng Wang, Yichun Cheng, Jiahe Fan, Ran Luo, Gang Xu, Shuwang Ge
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-024-01026-z