Robust nucleation control via crisscross polymerization of highly coordinated DNA slats

For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, provi...

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Bibliographic Details
Main Authors: Dionis Minev, Christopher M. Wintersinger, Anastasia Ershova, William M. Shih
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21755-7