Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, provi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21755-7 |
| _version_ | 1818435192284512256 |
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| author | Dionis Minev Christopher M. Wintersinger Anastasia Ershova William M. Shih |
| author_facet | Dionis Minev Christopher M. Wintersinger Anastasia Ershova William M. Shih |
| author_sort | Dionis Minev |
| collection | DOAJ |
| description | For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, providing strictly seed-initiated nucleation of crisscross ribbons with distinct widths and twists. |
| first_indexed | 2024-12-14T16:48:58Z |
| format | Article |
| id | doaj.art-2c2609169ffc489a95495823973de4eb |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T16:48:58Z |
| publishDate | 2021-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-2c2609169ffc489a95495823973de4eb2022-12-21T22:54:07ZengNature PortfolioNature Communications2041-17232021-03-011211910.1038/s41467-021-21755-7Robust nucleation control via crisscross polymerization of highly coordinated DNA slatsDionis Minev0Christopher M. Wintersinger1Anastasia Ershova2William M. Shih3John A. Paulson School of Engineering and Applied Sciences, Harvard UniversityJohn A. Paulson School of Engineering and Applied Sciences, Harvard UniversityWyss Institute for Biologically Inspired Engineering at Harvard UniversityWyss Institute for Biologically Inspired Engineering at Harvard UniversityFor programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, providing strictly seed-initiated nucleation of crisscross ribbons with distinct widths and twists.https://doi.org/10.1038/s41467-021-21755-7 |
| spellingShingle | Dionis Minev Christopher M. Wintersinger Anastasia Ershova William M. Shih Robust nucleation control via crisscross polymerization of highly coordinated DNA slats Nature Communications |
| title | Robust nucleation control via crisscross polymerization of highly coordinated DNA slats |
| title_full | Robust nucleation control via crisscross polymerization of highly coordinated DNA slats |
| title_fullStr | Robust nucleation control via crisscross polymerization of highly coordinated DNA slats |
| title_full_unstemmed | Robust nucleation control via crisscross polymerization of highly coordinated DNA slats |
| title_short | Robust nucleation control via crisscross polymerization of highly coordinated DNA slats |
| title_sort | robust nucleation control via crisscross polymerization of highly coordinated dna slats |
| url | https://doi.org/10.1038/s41467-021-21755-7 |
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