Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury

Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury

Background: Our previous study showed that vitamin D (VD)-vitamin D receptor (VDR) plays a nephroprotective role in lipopolysaccharide (LPS)-induced acute kidney injury (AKI). Recently, glucose metabolism reprogramming was reported to be involved in the pathogenesis of AKI.Objective: To investigate...

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Bibliographic Details
Main Authors: Qing Dai, Hao Zhang, Shiqi Tang, Xueqin Wu, Jianwen Wang, Bin Yi, Jishi Liu, Zhi Li, Qin Liao, Aimei Li, Yan Liu, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Physiology
Subjects:
vitamin D
vitamin D receptor
glucose metabolism reprogramming
acute kidney injury
PDHA1 phosphorylation
AMPK pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1083643/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1083643/full

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