Opposite effect of polyamines on In vitro gene expression: Enhancement at low concentrations but inhibition at high concentrations.

Polyamines have various biological functions including marked effects on the structure and function of genomic DNA molecules. Changes in the higher-order structure of DNA caused by polyamines are expected to be closely related to genetic activity. To clarify this issue, we examined the relationship...

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Bibliographic Details
Main Authors: Ai Kanemura, Yuko Yoshikawa, Wakao Fukuda, Kanta Tsumoto, Takahiro Kenmotsu, Kenichi Yoshikawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5832264?pdf=render