Antiepileptogenic and Neuroprotective Effects of Pergularia daemia on Pilocarpine Model of Epilepsy

Antiepileptogenic and Neuroprotective Effects of Pergularia daemia on Pilocarpine Model of Epilepsy

In this study, we investigated antiepileptogenic and neuroprotective effects of the aqueous extract of Pergularia daemia roots (PDR) using in vivo and in vitro experimental models. In in vivo studies, status epilepticus caused by pilocarpine injection triggers epileptogenesis which evolves during ab...

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Bibliographic Details
Main Authors: Antoine K. Kandeda, Germain S. Taiwe, Fleur C. O. Moto, Gwladys T. Ngoupaye, Gisele C. N. Nkantchoua, Jacqueline S. K. Njapdounke, Jean P. O. Omam, Simon Pale, Nadege Kouemou, Elisabeth Ngo Bum
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
antiepileptogenic
antioxidant
neuroprotective
Pergularia daemia
pilocarpine
status epilepticus
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00440/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00440/full

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