Connexin Mutants Cause Cataracts Through Deposition of Apatite

Cataracts are lens opacities that are among the most common causes of blindness. It is commonly believed that cataracts develop through the accumulation of damage to lens proteins. However, recent evidence suggests that cataracts can result from calcium ion accumulation and the precipitation of calc...

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Bibliographic Details
Main Authors: Peter J. Minogue, Andre J. Sommer, James C. Williams, Sharon B. Bledsoe, Eric C. Beyer, Viviana M. Berthoud
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.951231/full