The structural patterns of the potentiation and the blockade of inhibitory <i>cys</i>-loop receptors through the transmembrane domain

Anion-conducting cys-loop receptors activated by -aminobutyric acid (GABAАRs) and glycine (GlyRs) have inhibitory activity in the brain and spinal cord. GABAАRs and GlyRs are targets for various substances that potentiate or inhibit the receptor functions. Many of these substances are clinically sig...

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Bibliographic Details
Main Author: Alexey V. Rossokhin
Format: Article
Language:English
Published: Research Center of Neurology 2022-12-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/838/pdf