Sunitinib Does Not Accelerate Tumor Growth in Patients with Metastatic Renal Cell Carcinoma

Preclinical studies have suggested that sunitinib accelerates metastases in animals, ascribing this to inhibition of the vascular endothelial growth factor receptor or the tumor’s adaptation. To address whether sunitinib accelerates tumors in humans, we analyzed data from the pivotal randomized phas...

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Bibliographic Details
Main Authors: Krastan B. Blagoev, Julia Wilkerson, Wilfred D. Stein, Robert J. Motzer, Susan E. Bates, A. Tito Fojo
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000223