Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trialResearch in context

Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trialResearch in context

Summary: Background: Healthcare-associated infections account for substantial neonatal in-hospital mortality. Chlorhexidine gluconate (CHG) whole body skin application could reduce sepsis by lowering bacterial colonisation density, although safety and optimal application regimen is unclear. Emollie...

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Bibliographic Details
Main Authors: Neal Russell, Michelle N. Clements, Kazi Shammin Azmery, Adrie Bekker, Julia Bielicki, Angela Dramowski, Sally Ellis, Aaqilah Fataar, Mahbubul Hoque, Kristen LeBeau, Seamus O’Brien, Francesca Schiavone, Peter Skoutari, Mohammad Shahidul Islam, Samir K. Saha, Ann Sarah Walker, Andrew Whitelaw, Michael Sharland
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:EClinicalMedicine
Subjects:
Neonatal sepsis
Infection prevention
Antiseptic
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537024000427

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http://www.sciencedirect.com/science/article/pii/S2589537024000427

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