Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay

Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay

Background Mortality for infants undergoing complex cardiac surgery is >10% with a 30% to 40% risk of complications. Early identification and treatment of high‐risk infants remains challenging. Metabolites are small molecules that determine the minute‐to‐minute cellular phenotype, making them ide...

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Bibliographic Details
Main Authors: Jesse A. Davidson, Zachary Pfeifer, Benjamin Frank, Suhong Tong, Tracy T. Urban, Paul A. Wischmeyer, Peter Mourani, Bruce Landeck, Uwe Christians, Jelena Klawitter
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
congenital heart disease
critical care
kynurenic acid
metabolite
metabolome
methylnicotinamide
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010711

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.010711

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