BRCA in Gastrointestinal Cancers: Current Treatments and Future Perspectives

BRCA in Gastrointestinal Cancers: Current Treatments and Future Perspectives

A strong association between pancreatic cancer and <i>BRCA1</i> and <i>BRCA2</i> mutations is documented. Based on promising results of breast and ovarian cancers, several clinical trials with poly (ADP-ribose) polymerase inhibitors (PARPi) are ongoing for gastrointestinal (G...

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Bibliographic Details
Main Authors: Eleonora Molinaro, Kalliopi Andrikou, Andrea Casadei-Gardini, Giulia Rovesti
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
BRCA1
BRCA2
gastrointestinal cancers
HRD
pancreatic cancer
Olaparib
Online Access:https://www.mdpi.com/2072-6694/12/11/3346

Internet

https://www.mdpi.com/2072-6694/12/11/3346

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