Identification of myoferlin as a mitochondria-associated membranes component required for calcium signaling in PDAC cell lines

Identification of myoferlin as a mitochondria-associated membranes component required for calcium signaling in PDAC cell lines

Abstract Background Pancreatic ductal adenocarcinoma is an aggressive cancer type with one of the lowest survival rates due to late diagnosis and the absence of effective treatments. A better understanding of PDAC biology will help researchers to discover the Achilles’ heel of cancer cells. In that...

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Bibliographic Details
Main Authors: Sandy Anania, Martin Farnir, Raphaël Peiffer, Yasmine Boumahd, Marc Thiry, Ferman Agirman, Naima Maloujahmoum, Akeila Bellahcène, Olivier Peulen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Pancreatic cancer
Mitochondria-associated membranes
ER-mitochondria contact sites
Myoferlin
Calcium signaling
IP3R3
Online Access:https://doi.org/10.1186/s12964-024-01514-z

Internet

https://doi.org/10.1186/s12964-024-01514-z

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