Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

Worldwide, the number of cancer-related deaths continues to increase due to the ability of cancer cells to become chemotherapy-resistant and metastasize. For women with ovarian cancer, a staggering 70% will become resistant to the front-line therapy, cisplatin. Although many mechanisms of cisplatin...

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Bibliographic Details
Main Authors: Robert J. Rabelo-Fernández, Ginette S. Santiago-Sánchez, Rohit K. Sharma, Abiel Roche-Lima, Kelvin Carrasquillo Carrion, Ricardo A. Noriega Rivera, Blanca I. Quiñones-Díaz, Swetha Rajasekaran, Jalal Siddiqui, Wayne Miles, Yasmarie Santana Rivera, Fatima Valiyeva, Pablo E. Vivas-Mejia
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
RNA binding protein with multiple splicing
ovarian cancer
CRISPR
cisplatin resistance
tumor suppressor gene
Online Access:https://www.mdpi.com/1422-0067/23/1/535

Internet

https://www.mdpi.com/1422-0067/23/1/535

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