Strain Mediated Adaptation Is Key for Myosin Mechanochemistry: Discovering General Rules for Motor Activity.

A structure-based model of myosin motor is built in the same spirit of our early work for kinesin-1 and Ncd towards physical understanding of its mechanochemical cycle. We find a structural adaptation of the motor head domain in post-powerstroke state that signals faster ADP release from it compared...

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Bibliographic Details
Main Authors: Biman Jana, José N Onuchic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4975490?pdf=render