Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins
Abstract High levels of HDL-C are correlated with a decreased risk of cardiovascular disease. HDL-C levels are modulated in part by the secreted phospholipase, endothelial lipase (EL), which hydrolyzes the phospholipids of HDL and decreases circulating HDL-C concentrations. A 584C/T polymorphism in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-54705-6 |