Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins

Abstract High levels of HDL-C are correlated with a decreased risk of cardiovascular disease. HDL-C levels are modulated in part by the secreted phospholipase, endothelial lipase (EL), which hydrolyzes the phospholipids of HDL and decreases circulating HDL-C concentrations. A 584C/T polymorphism in...

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Bibliographic Details
Main Authors: Kelli L. Sylvers-Davie, Kaleb C. Bierstedt, Michael J. Schnieders, Brandon S. J. Davies
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-54705-6