Dissecting clinical and biological heterogeneity in clinical states of bipolar disorder: a 10-year retrospective study from China

Dissecting clinical and biological heterogeneity in clinical states of bipolar disorder: a 10-year retrospective study from China

ObjectivesTo dissect clinical and biological heterogeneity in clinical states of bipolar disorder (BD), and investigate if neuropsychological symptomatology, comorbidity, vital signs, and blood laboratory indicators are predictors of distinct BD states.MethodsA retrospective BD cohort was establishe...

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Bibliographic Details
Main Authors: Ting Zhu, Ran Kou, Yao Hu, Minlan Yuan, Cui Yuan, Li Luo, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Psychiatry
Subjects:
bipolar disorder
biological heterogeneity
clinical states
machine learning
electronic medical records (EMR)
Shapley additive explanations (SHAP)
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1128862/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1128862/full

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