Dendritic cells under allergic condition enhance the activation of pruritogen-responsive neurons via inducing itch receptors in a co-culture study

Dendritic cells under allergic condition enhance the activation of pruritogen-responsive neurons via inducing itch receptors in a co-culture study

Abstract Background Itch sensitization has been reported in patients with chronic allergic skin diseases and observed in a mouse model of allergic contact dermatitis (ACD). There is evidence suggesting that neuroimmune interactions may contribute to itch sensitization, as an increase in dendritic ce...

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Bibliographic Details
Main Authors: Tichakorn Singto, Viviane Filor, Jonathan Vidak, Robert Klopfleisch, Wolfgang Bäumer
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Immunology
Subjects:
Dendritic cell
Dorsal root ganglia
Peripheral sensitization
Itch
Pruritus
Allergic contact dermatitis
Online Access:https://doi.org/10.1186/s12865-024-00604-4

Internet

https://doi.org/10.1186/s12865-024-00604-4

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