Targeting stearoyl-coa desaturase enhances radiation induced ferroptosis and immunogenic cell death in esophageal squamous cell carcinoma

Targeting stearoyl-coa desaturase enhances radiation induced ferroptosis and immunogenic cell death in esophageal squamous cell carcinoma

Overcoming resistance to radiation is a major challenge in cancer treatment. Stearoyl-coa desaturase (SCD1) is the enzyme responsible for oleic acid (OA) and palmitoleic acid (POA) formation. Here, we provided evidence that targeting SCD1 was capable of inducing ferroptosis and immunogenic cell deat...

Full description

Bibliographic Details
Main Authors: Hui Luo, Xiaohui Wang, Shuai Song, Yunhan Wang, Qinfu Dan, Hong Ge
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
Esophageal cancer
SCD1 inhibitor
radiation therapy
ferroptosis
immunogenic cell death
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2101769

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2022.2101769

Similar Items