BDNF activates mTOR to regulate GluR1 expression required for memory formation.
BACKGROUND:The mammalian target of Rapamycin (mTOR) kinase plays a key role in translational control of a subset of mRNAs through regulation of its initiation step. In neurons, mTOR is present at the synaptic region, where it modulates the activity-dependent expression of locally-translated proteins...
| Hoofdauteurs: | , , , , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2009-06-01
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| Reeks: | PLoS ONE |
| Online toegang: | http://europepmc.org/articles/PMC2695538?pdf=render |