A Novel Histological Technique to Assess Severity of Traumatic Brain Injury in Rodents: Comparisons to Neuroimaging and Neurological Outcomes

Here we evaluate an alternative protocol to histologically examine blood-brain barrier (BBB) breakdown, brain edema, and lesion volume following traumatic brain injury (TBI) in the same set of rodent brain samples. We further compare this novel histological technique to measurements determined by ma...

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Bibliographic Details
Main Authors: Dmitry Frank, Benjamin F. Gruenbaum, Ilan Shelef, Vladislav Zvenigorodsky, Yair Benjamin, Olha Shapoval, Ron Gal, Alexander Zlotnik, Israel Melamed, Matthew Boyko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.733115/full