Increased P450 aromatase levels in post-menopausal women after acute ischemic stroke

Abstract Background Sex differences in stroke have been attributed to the neuroprotective effects of estrogen, yet most clinical trials of estrogen supplementation for stroke prevention have failed. The contribution of sex hormones to stroke outcome remains a subject of debate. Aromatization of test...

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Bibliographic Details
Main Authors: Bharti Manwani, Pamela Fall, Liang Zhu, Meaghan Roy O’Reilly, Sarah Conway, Ilene Staff, Louise D. McCullough
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-020-00357-w