Multi-task learning to leverage partially annotated data for PPI interface prediction

Abstract Protein protein interactions (PPI) are crucial for protein functioning, nevertheless predicting residues in PPI interfaces from the protein sequence remains a challenging problem. In addition, structure-based functional annotations, such as the PPI interface annotations, are scarce: only fo...

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Bibliographic Details
Main Authors: Henriette Capel, K. Anton Feenstra, Sanne Abeln
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13951-2