Combined Immune Defect in B-Cell Lymphoproliferative Disorders Is Associated with Severe Infection and Cancer Progression

Combined Immune Defect in B-Cell Lymphoproliferative Disorders Is Associated with Severe Infection and Cancer Progression

B cell chronic lymphoproliferative diseases (B-CLPD) are associated with secondary antibody deficiency and other innate and adaptive immune defects, whose impact on infectious risk has not been systematically addressed. We performed an immunological analysis of a cohort of 83 B-CLPD patients with re...

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Bibliographic Details
Main Authors: Juliana Ochoa-Grullón, Kissy Guevara-Hoyer, Cristina Pérez López, Rebeca Pérez de Diego, Ascensión Peña Cortijo, Marta Polo, Marta Mateo Morales, Eduardo Anguita Mandley, Carlos Jiménez García, Estefanía Bolaños, Belén Íñigo, Fiorella Medina, Antonia Rodríguez de la Peña, Carmen Izquierdo Delgado, Eduardo de la Fuente Muñoz, Elsa Mayol, Miguel Fernández-Arquero, Ataúlfo González-Fernández, Celina Benavente Cuesta, Silvia Sánchez-Ramón
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
B cell chronic lymphoproliferative disorders
severe infections
secondary immunodeficiency
predominantly antibody defect
combine immune defect
cancer progression
Online Access:https://www.mdpi.com/2227-9059/10/8/2020

Internet

https://www.mdpi.com/2227-9059/10/8/2020

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