RNA-based therapy in the management of lipid disorders: a review

RNA-based therapy in the management of lipid disorders: a review

Abstract This review focuses on antisense oligonucleotides and small interfering ribonucleic acid therapies approved or under development for the management of lipid disorders. Recent advances in RNA-based therapeutics allow tissue-specific targeting improving safety. Multiple potential target prote...

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Bibliographic Details
Main Authors: Dirk Jacobus Blom, Adrian David Marais, Rajen Moodley, Nico van der Merwe, Alet van Tonder, Frederick Johan Raal
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Lipids in Health and Disease
Subjects:
RNA-based therapies
Lipid disorders
Small interfering RNA
Antisense oligonucleotides
Lipid-lowering
LDL-C
Online Access:https://doi.org/10.1186/s12944-022-01649-3

Internet

https://doi.org/10.1186/s12944-022-01649-3

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