In vitro and in silico perspectives on the activation of antioxidant responsive element by citrus-derived flavonoids

IntroductionOxidative stress plays an essential role in the pathogenesis of chronic diseases. Disrupting the Keap1-Nrf2 pathway by binding Keap1 is identified as a potential strategy to prevent oxidative stress-related chronic diseases. Therefore, of special interest is the utilization of dietary an...

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Bibliographic Details
Main Authors: Tianzhu Guan, Canfeng Bian, Zheng Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1257172/full