An integrated bioinformatics approach to identify key biomarkers in the tubulointerstitium of patients with focal segmental glomerulosclerosis and construction of mRNA–miRNA-lncRNA/circRNA networks

An integrated bioinformatics approach to identify key biomarkers in the tubulointerstitium of patients with focal segmental glomerulosclerosis and construction of mRNA–miRNA-lncRNA/circRNA networks

AbstractObjective The purpose of this study was to identify potential biomarkers in the tubulointerstitium of focal segmental glomerulosclerosis (FSGS) and comprehensively analyze its mRNA–miRNA-lncRNA/circRNA network.Methods The expression data (GSE108112 and GSE200818) were downloaded from the Gen...

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Bibliographic Details
Main Authors: Yun Xia Zhang, Jun Yuan Bai, XiaoWei Pu, Juan Lv, En Lai Dai
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
Focal segmental glomerulosclerosis
tubulointerstitium
weighted gene coexpression network analysis
least absolute shrinkage and selection operator
PPARGC1A
mRNA–miRNA-lncRNA/circRNA network
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2023.2284212

Internet

https://www.tandfonline.com/doi/10.1080/0886022X.2023.2284212

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