The X-ray Crystal Structure of Full-Length Human Plasminogen

The X-ray Crystal Structure of Full-Length Human Plasminogen

Plasminogen is the proenzyme precursor of the primary fibrinolytic protease plasmin. Circulating plasminogen, which comprises a Pan-apple (PAp) domain, five kringle domains (KR1-5), and a serine protease (SP) domain, adopts a closed, activation-resistant conformation. The kringle domains mediate int...

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Bibliographic Details
Main Authors: Ruby H.P. Law, Tom Caradoc-Davies, Nathan Cowieson, Anita J. Horvath, Adam J. Quek, Joanna Amarante Encarnacao, David Steer, Angus Cowan, Qingwei Zhang, Bernadine G.C. Lu, Robert N. Pike, A. Ian Smith, Paul B. Coughlin, James C. Whisstock
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712000691

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http://www.sciencedirect.com/science/article/pii/S2211124712000691

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