Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway

Summary: Osteocytes are the mechano-sensors of bones. Large gradient high-static magnetic fields (LG-HMFs) produce stable, high-precision, and non-attenuation mechanical forces. We discovered that magnetic forces opposite to gravity inhibited MLO-Y4 osteocyte proliferation and viability by inducing...

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Bibliographic Details
Main Authors: Bin Zhang, Xianglin Li, Xiaojie Zhou, ChenGe Lou, Shenghang Wang, Huanhuan Lv, Gejing Zhang, Yanwen Fang, Dachuan Yin, Peng Shang
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014426