Structural basis for amino acid transport by the CAT family of SLC7 transporters

Cationic amino acid transporters (CATs) belong to the physiologically important solute carrier (SLC) 7 family. Here, the authors present the structure of the mammalian CAT transporter homologue Geobacillus kaustophilus GkApcT, which reveals how arginine is recognized, and propose a model for proton-...

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Bibliographic Details
Main Authors: Katharina E. J. Jungnickel, Joanne L. Parker, Simon Newstead
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03066-6