A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling

A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling

Abstract In the liver, mitochondria are exposed to different concentrations of nutrients due to their spatial positioning across the periportal and pericentral axis. How the mitochondria sense and integrate these signals to respond and maintain homeostasis is not known. Here, we combine intravital m...

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Bibliographic Details
Main Authors: Sun Woo Sophie Kang, Rory P. Cunningham, Colin B. Miller, Lauryn A. Brown, Constance M. Cultraro, Adam Harned, Kedar Narayan, Jonathan Hernandez, Lisa M. Jenkins, Alexei Lobanov, Maggie Cam, Natalie Porat-Shliom
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45751-9

Internet

https://doi.org/10.1038/s41467-024-45751-9

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