Sensitivity and Specificity of CD19.CAR-T Cell Detection by Flow Cytometry and PCR

Sensitivity and Specificity of CD19.CAR-T Cell Detection by Flow Cytometry and PCR

Chimeric-antigen-receptor-T (CAR-T) cells are currently revolutionizing the field of cancer immunotherapy. Therefore, there is an urgent need for CAR-T cell monitoring by clinicians to assess cell expansion and persistence in patients. CAR-T cell manufacturers and researchers need to evaluate transd...

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Bibliographic Details
Main Authors: Nicola Schanda, Tim Sauer, Alexander Kunz, Angela Hückelhoven-Krauss, Brigitte Neuber, Lei Wang, Mandy Hinkelbein, David Sedloev, Bailin He, Maria-Luisa Schubert, Carsten Müller-Tidow, Michael Schmitt, Anita Schmitt
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
CD19.CAR-T cells
flow cytometry (FACS)
polymerase chain reaction (PCR)
detection reagent
Online Access:https://www.mdpi.com/2073-4409/10/11/3208

Internet

https://www.mdpi.com/2073-4409/10/11/3208

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