Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure

Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure

AbstractThe Toll-like receptor (TLR) adaptor protein MyD88 is integral to airway inflammatory response to microbial-enriched organic dust extract (ODE) exposures. ODE-induced airway neutrophil influx and release of pro-inflammatory cytokines was essentially abrogated in global MyD88-deficient mice,...

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Bibliographic Details
Main Authors: Amber N. Johnson, John Dickinson, Amy Nelson, Rohit Gaurav, Katrina Kudrna, Scott E. Evans, Katherine Janike, Todd A. Wyatt, Jill A. Poole
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Immunotoxicology
Subjects:
Environmental respiratory disease
agriculture
occupational
organic dust
airway inflammation
adaptation
Online Access:https://www.tandfonline.com/doi/10.1080/1547691X.2022.2148782

Internet

https://www.tandfonline.com/doi/10.1080/1547691X.2022.2148782

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