Bench-to-Bedside Studies of Arginine Deprivation in Cancer

Arginine is a semi-essential amino acid which becomes wholly essential in many cancers commonly due to the functional loss of Argininosuccinate Synthetase 1 (ASS1). As arginine is vital for a plethora of cellular processes, its deprivation provides a rationale strategy for combatting arginine-depend...

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Bibliographic Details
Main Authors: George C. Field, Iuliia Pavlyk, Peter W. Szlosarek
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/5/2150