Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment

Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment

Both early life aversive experiences and intrinsic alterations in early postnatal neurodevelopment are considered predisposing factors for psychiatric disorders, such as schizophrenia. The prefrontal cortex and the hippocampus have protracted postnatal development and are affected in schizophrenic p...

Full description

Bibliographic Details
Main Authors: Patrycja Klimczak, Arianna Rizzo, Esther Castillo-Gómez, Marta Perez-Rando, Yaiza Gramuntell, Marc Beltran, Juan Nacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
schizophrenia
parvalbumin
interneuron
social isolation
early aversive experience
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.733989/full

Internet

https://www.frontiersin.org/articles/10.3389/fnsyn.2021.733989/full

Similar Items