Quantifying the adaptive landscape of commensal gut bacteria using high-resolution lineage tracking

Abstract Gut microbiota can adapt to their host environment by rapidly acquiring new mutations. However, the dynamics of this process are difficult to characterize in dominant gut species in their complex in vivo environment. Here we show that the fine-scale dynamics of genome-wide transposon librar...

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Bibliographic Details
Main Authors: Daniel P. G. H. Wong, Benjamin H. Good
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45792-0