Interleukin-18 in chronic pain: Focus on pathogenic mechanisms and potential therapeutic targets

Chronic pain has been proven to be an independent disease, other than an accompanying symptom of certain diseases. Interleukin-18 (IL-18), a pro-inflammatory cytokine with pleiotropic biological effects, participates in immune modulation, inflammatory response, tumor growth, as well as the process o...

Full description

Bibliographic Details
Main Authors: Jie Ju, Zheng Li, Xiaoqian Jia, Xiaoling Peng, Jihong Wang, Feng Gao
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824000331