Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice
Abstract Mutations in the X-linked gene Protocadherin-19 (Pcdh19) cause female-limited epilepsy and mental retardation in humans. Although Pcdh19 is known to be a homophilic cell-cell adhesion molecule, how its mutations bring about female-specific disorders remains elusive. Here, we report the effe...
| Auteurs principaux: | , , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Nature Portfolio
2017-07-01
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| Collection: | Scientific Reports |
| Accès en ligne: | https://doi.org/10.1038/s41598-017-06374-x |